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Publications
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Di Fonzo A, Rohé CF, Ferreira J, Chien HF, Vacca L, Stocchi F, Guedes L, Fabrizio E, Manfredi M, Vanacore N, Goldwurm S, Breedveld G, Sampaio C, Meco G, Barbosa E, Oostra BA, Bonifati V; Italian Parkinson Genetics Network. A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease. Lancet 365: 412-5, 2005 (PubMed ID: 15680456) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 41 | |
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Gilks WP, Abou-Sleiman PM, Gandhi S, Jain S, Singleton A, Lees AJ, Shaw K, Bhatia KP, Bonifati V, Quinn NP, Lynch J, Healy DG, Holton JL, Revesz T, Wood NW. A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 365: 415-6, 2005 (PubMed ID: 15680457) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 42 | |
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Nichols WC, Pankratz N, Hernandez D, Paisán-Ruíz C, Jain S, Halter CA, Michaels VE, Reed T, Rudolph A, Shults CW, Singleton A, Foroud T; Parkinson Study Group-PROGENI investigators. Genetic screening for a single common LRRK2 mutation in familial Parkinson's disease. Lancet 365: 410-2, 2005 (PubMed ID: 15680455) |
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LRRK2:
(Gly2019Ser)
|
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ID: 43 | |
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Hernandez DG, Paisán-Ruíz C, McInerney-Leo A, Jain S, Meyer-Lindenberg A, Evans EW, Berman KF, Johnson J, Auburger G, Schäffer AA, Lopez GJ, Nussbaum RL, Singleton AB. Clinical and positron emission tomography of Parkinson's disease caused by LRRK2. Ann Neurol 57: 453-6, 2005 (PubMed ID: 15732108) |
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LRRK2:
(Gly2019Ser)
|
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ID: 83 | |
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Kachergus J, Mata IF, Hulihan M, Taylor JP, Lincoln S, Aasly J, Gibson JM, Ross OA, Lynch T, Wiley J, Payami H, Nutt J, Maraganore DM, Czyzewski K, Styczynska M, Wszolek ZK, Farrer MJ, Toft M. Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations. Am J Hum Genet 76: 672-80, 2005 (PubMed ID: 15726496) |
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LRRK2:
(Gly2019Ser)
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ID: 50 | |
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Aasly JO, Toft M, Fernandez-Mata I, Kachergus J, Hulihan M, White LR, Farrer M. Clinical features of LRRK2-associated Parkinson's disease in central Norway. Ann Neurol 57: 762-5, 2005 (PubMed ID: 15852371) |
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LRRK2:
(Gly2019Ser)
|
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ID: 68 | |
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Deng H, Le W, Guo Y, Hunter CB, Xie W, Jankovic J. Genetic and clinical identification of Parkinson's disease patients with LRRK2 G2019S mutation. Ann Neurol 57: 933-4, 2005 (PubMed ID: 15929036) |
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LRRK2:
(Gly2019Ser)
|
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ID: 60 | |
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Kay DM, Kramer P, Higgins D, Zabetian CP, Payami H. Escaping Parkinson's disease: a neurologically healthy octogenarian with the LRRK2 G2019S mutation. Mov Disord 20: 1077-8, 2005 (PubMed ID: 16001413) |
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LRRK2:
(Gly2019Ser)
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ID: 63 | |
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Lesage S, Leutenegger AL, Ibanez P, Janin S, Lohmann E, Dürr A, Brice A; French Parkinson's Disease Genetics Study Group. LRRK2 haplotype analyses in European and North African families with Parkinson disease: a common founder for the G2019S mutation dating from the 13th century. Am J Hum Genet 77: 330-2, 2005 (PubMed ID: 16145815) |
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LRRK2:
(Gly2019Ser)
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ID: 65 | |
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Gosal D, Ross OA, Wiley J, Irvine GB, Johnston JA, Toft M, Mata IF, Kachergus J, Hulihan M, Taylor JP, Lincoln SJ, Farrer MJ, Lynch T, Mark Gibson J. Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD. Parkinsonism Relat Disord 11: 349-52, 2005 (PubMed ID: 16102999) |
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LRRK2:
(Gly2019Ser)
|
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ID: 67 | |
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Farrer M, Stone J, Mata IF, Lincoln S, Kachergus J, Hulihan M, Strain KJ, Maraganore DM. LRRK2 mutations in Parkinson disease. Neurology 65: 738-40, 2005 (PubMed ID: 16157908) |
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LRRK2:
(Arg793Met)
(Leu1114)
(Met1869Thr)
(Gly2019Ser)
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ID: 46 | |
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Paisán-Ruíz C, Lang AE, Kawarai T, Sato C, Salehi-Rad S, Fisman GK, Al-Khairallah T, St George-Hyslop P, Singleton A, Rogaeva E. LRRK2 gene in Parkinson disease: mutation analysis and case control association study. Neurology 65: 696-700, 2005 (PubMed ID: 16157901) |
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LRRK2:
(Leu953)
(Ile1371Val)
(Arg1398His)
(Gly1624)
(Gly2019Ser)
(Met2397Thr)
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ID: 57 | |
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Zabetian CP, Samii A, Mosley AD, Roberts JW, Leis BC, Yearout D, Raskind WH, Griffith A. A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations. Neurology 65: 741-4, 2005 (PubMed ID: 16157909) |
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LRRK2:
(Arg1441Cys)
(Arg1441His)
(IVS31+3A>G)
(Gly2019Ser)
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ID: 59 | |
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Goldwurm S, Di Fonzo A, Simons EJ, Rohé CF, Zini M, Canesi M, Tesei S, Zecchinelli A, Antonini A, Mariani C, Meucci N, Sacilotto G, Sironi F, Salani G, Ferreira J, Chien HF, Fabrizio E, Vanacore N, Dalla Libera A, Stocchi F, Diroma C, Lamberti P, Sampaio C, Meco G, Barbosa E, Bertoli-Avella AM, Breedveld GJ, Oostra BA, Pezzoli G, Bonifati V. The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor. J Med Genet 42: e65, 2005 (PubMed ID: 16272257) |
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LRRK2:
(Arg1441Cys)
(Gly2019Ser)
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ID: 61 | |
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Lesage S, Ibanez P, Lohmann E, Pollak P, Tison F, Tazir M, Leutenegger AL, Guimaraes J, Bonnet AM, Agid Y, Dürr A, Brice A; French Parkinson's Disease Genetics Study Group. G2019S LRRK2 mutation in French and North African families with Parkinson's disease. Ann Neurol 58: 784-7, 2005 (PubMed ID: 16240353) |
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LRRK2:
(Gly2019Ser)
|
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ID: 64 | |
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Biskup S, Mueller JC, Sharma M, Lichtner P, Zimprich A, Berg D, Wüllner U, Illig T, Meitinger T, Gasser T. Common variants of LRRK2 are not associated with sporadic Parkinson's disease. Ann Neurol 58: 905-8, 2005 (PubMed ID: 16254973) |
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LRRK2:
(Gly2019Ser)
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ID: 66 | |
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Bras JM, Guerreiro RJ, Ribeiro MH, Januario C, Morgadinho A, Oliveira CR, Cunha L, Hardy J, Singleton A. G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort. Mov Disord 20: 1653-5, 2005 (PubMed ID: 16149095) |
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LRRK2:
(Gly2019Ser)
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ID: 45 | |
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Khan NL, Jain S, Lynch JM, Pavese N, Abou-Sleiman P, Holton JL, Healy DG, Gilks WP, Sweeney MG, Ganguly M, Gibbons V, Gandhi S, Vaughan J, Eunson LH, Katzenschlager R, Gayton J, Lennox G, Revesz T, Nicholl D, Bhatia KP, Quinn N, Brooks D, Lees AJ, Davis MB, Piccini P, Singleton AB, Wood NW. Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain 128: 2786-96, 2005 (PubMed ID: 16272164) |
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LRRK2:
(Tyr1699Cys)
(Arg1941His)
(Gly2019Ser)
(Thr2356Ile)
|
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ID: 51 | |
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Mata IF, Kachergus JM, Taylor JP, Lincoln S, Aasly J, Lynch T, Hulihan MM, Cobb SA, Wu RM, Lu CS, Lahoz C, Wszolek ZK, Farrer MJ. Lrrk2 pathogenic substitutions in Parkinson's disease. Neurogenetics 6: 171-7, 2005 (PubMed ID: 16172858) |
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LRRK2:
(Leu153)
(Lys182)
(Ser461)
(Asn551Lys)
(Ile723Val)
(Lys1423)
(Arg1441Gly)
(Arg1441Cys)
(Arg1441His)
(Arg1514Gln)
(Pro1542Ser)
(Arg1628Pro)
(Lys1637)
(Met1646Thr)
(Ser1647Thr)
(Gly1819)
(Met1869Thr)
(Gly2019Ser)
(Glu2108)
(Gly2170)
(Gly2385Arg)
(Gly2385)
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ID: 56 | |
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Hernandez D, Paisan Ruiz C, Crawley A, Malkani R, Werner J, Gwinn-Hardy K, Dickson D, Wavrant Devrieze F, Hardy J, Singleton A. The dardarin G 2019 S mutation is a common cause of Parkinson's disease but not other neurodegenerative diseases. Neurosci Lett 389: 137-9, 2005 (PubMed ID: 16102903) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 62 | |
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Lesage S, Dürr A, Tazir M, Lohmann E, Leutenegger AL, Janin S, Pollak P, Brice A; French Parkinson's Disease Genetics Study Group. LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med 354: 422-3, 2006 (PubMed ID: 16436781) |
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LRRK2:
(Gly2019Ser)
|
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ID: 90 | |
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Ozelius LJ, Senthil G, Saunders-Pullman R, Ohmann E, Deligtisch A, Tagliati M, Hunt AL, Klein C, Henick B, Hailpern SM, Lipton RB, Soto-Valencia J, Risch N, Bressman SB. LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med 354: 424-5, 2006 (PubMed ID: 16436782) |
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LRRK2:
(Gly2019Ser)
|
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ID: 92 | |
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Giasson BI, Covy JP, Bonini NM, Hurtig HI, Farrer MJ, Trojanowski JQ, Van Deerlin VM. Biochemical and pathological characterization of Lrrk2. Ann Neurol 59: 315-22, 2006 (PubMed ID: 16437584) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 107 | |
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Ross OA, Toft M, Whittle AJ, Johnson JL, Papapetropoulos S, Mash DC, Litvan I, Gordon MF, Wszolek ZK, Farrer MJ, Dickson DW. Lrrk2 and Lewy body disease. Ann Neurol 59: 388-93, 2006 (PubMed ID: 16437559) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 100 | |
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Di Fonzo A, Tassorelli C, De Mari M, Chien HF, Ferreira J, Rohé CF, Riboldazzi G, Antonini A, Albani G, Mauro A, Marconi R, Abbruzzese G, Lopiano L, Fincati E, Guidi M, Marini P, Stocchi F, Onofrj M, Toni V, Tinazzi M, Fabbrini G, Lamberti P, Vanacore N, Meco G, Leitner P, Uitti RJ, Wszolek ZK, Gasser T, Simons EJ, Breedveld GJ, Goldwurm S, Pezzoli G, Sampaio C, Barbosa E, Martignoni E, Oostra BA, Bonifati V; Italian Parkinson's Genetics Network. Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease. Eur J Hum Genet 14: 322-31, 2006 (PubMed ID: 16333314) |
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LRRK2:
(Leu119Pro)
(IVS9-10C>A)
(IVS19-9_8insT)
(Ile1371Val)
(IVS30+12delT)
(Arg1441Cys)
(Arg1514Gln)
(Pro1542Ser)
(Met1646Thr)
(IVS37-9A>G)
(Gly2019Ser)
(IVS47-9delT)
(Gly2385)
|
|
ID: 72 | |
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Gaig C, Ezquerra M, Marti MJ, Muñoz E, Valldeoriola F, Tolosa E. LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance. Arch Neurol 63: 377-82, 2006 (PubMed ID: 16533964) |
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LRRK2:
(Arg1441Gly)
(Arg1441Cys)
(Gly2019Ser)
|
|
ID: 74 | |
|
Infante J, Rodríguez E, Combarros O, Mateo I, Fontalba A, Pascual J, Oterino A, Polo JM, Leno C, Berciano J. LRRK2 G2019S is a common mutation in Spanish patients with late-onset Parkinson's disease. Neurosci Lett 395: 224-6, 2006 (PubMed ID: 16298482) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 49 | |
|
Kay DM, Zabetian CP, Factor SA, Nutt JG, Samii A, Griffith A, Bird TD, Kramer P, Higgins DS, Payami H. Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics. Mov Disord 21: 519-23, 2006 (PubMed ID: 16250030) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 89 | |
|
Mata IF, Ross OA, Kachergus J, Huerta C, Ribacoba R, Moris G, Blazquez M, Guisasola LM, Salvador C, Martinez C, Farrer M, Alvarez V. LRRK2 mutations are a common cause of Parkinson's disease in Spain. Eur J Neurol 13: 391-4, 2006 (PubMed ID: 16643318) |
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|
LRRK2:
(Gly2019Ser)
|
|
ID: 76 | |
|
Williams-Gray CH, Goris A, Foltynie T, Brown J, Maranian M, Walton A, Compston DA, Sawcer SJ, Barker RA. Prevalence of the LRRK2 G2019S mutation in a UK community based idiopathic Parkinson's disease cohort. J Neurol Neurosurg Psychiatry 77: 665-7, 2006 (PubMed ID: 16614029) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 85 | |
|
Schlitter AM, Woitalla D, Mueller T, Epplen JT, Dekomien G. The LRRK2 gene in Parkinson's disease: mutation screening in patients from Germany. J Neurol Neurosurg Psychiatry 77: 891-2, 2006 (PubMed ID: 16788020) |
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|
LRRK2:
(Ala1151Thr)
(Gly2019Ser)
|
|
ID: 80 | |
|
Saunders-Pullman R, Lipton RB, Senthil G, Katz M, Costan-Toth C, Derby C, Bressman S, Verghese J, Ozelius LJ. Increased frequency of the LRRK2 G2019S mutation in an elderly Ashkenazi Jewish population is not associated with dementia. Neurosci Lett 402: 92-6, 2006 (PubMed ID: 16632201) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 94 | |
|
Isaias IU, Benti R, Goldwurm S, Zini M, Cilia R, Gerundini P, Di Fonzo A, Bonifati V, Pezzoli G, Antonini A. Striatal dopamine transporter binding in Parkinson's disease associated with the LRRK2 Gly2019Ser mutation. Mov Disord 21: 1144-7, 2006 (PubMed ID: 16671078) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 108 | |
|
Marongiu R, Ghezzi D, Ialongo T, Soleti F, Elia A, Cavone S, Albanese A, Altavista MC, Barone P, Brusa L, Cortelli P, Petrozzi L, Scaglione C, Stanzione P, Tinazzi M, Zeviani M, Dallapiccola B, Bentivoglio AR, Valente EM, Garavaglia B; Italian PD Study Group. Frequency and phenotypes of LRRK2 G2019S mutation in Italian patients with Parkinson's disease. Mov Disord 21: 1232-5, 2006 (PubMed ID: 16622859) |
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LRRK2:
(Gly2019Ser)
|
|
ID: 91 | |
|
Tomiyama H, Li Y, Funayama M, Hasegawa K, Yoshino H, Kubo S, Sato K, Hattori T, Lu CS, Inzelberg R, Djaldetti R, Melamed E, Amouri R, Gouider-Khouja N, Hentati F, Hatano Y, Wang M, Imamichi Y, Mizoguchi K, Miyajima H, Obata F, Toda T, Farrer MJ, Mizuno Y, Hattori N. Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries. Mov Disord 21: 1102-8, 2006 (PubMed ID: 16622854) |
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LRRK2:
(Ile2012Thr)
(Gly2019Ser)
(Ile2020Thr)
|
|
ID: 95 | |
|
Zabetian CP, Morino H, Ujike H, Yamamoto M, Oda M, Maruyama H, Izumi Y, Kaji R, Griffith A, Leis BC, Roberts JW, Yearout D, Samii A, Kawakami H. Identification and haplotype analysis of LRRK2 G2019S in Japanese patients with Parkinson disease. Neurology 67: 697-9, 2006 (PubMed ID: 16728648) |
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|
LRRK2:
(Gly2019Ser)
|
|
ID: 96 | |
|
Hedrich K, Winkler S, Hagenah J, Kabakci K, Kasten M, Schwinger E, Volkmann J, Pramstaller PP, Kostic V, Vieregge P, Klein C. Recurrent LRRK2 (Park8) mutations in early-onset Parkinson's disease. Mov Disord 21: 1506-10, 2006 (PubMed ID: 16758483) |
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LRRK2:
(Ala1151Thr)
(Arg1441Cys)
(Gly2019Ser)
|
|
ID: 75 | |
|
Ishihara L, Warren L, Gibson R, Amouri R, Lesage S, Dürr A, Tazir M, Wszolek ZK, Uitti RJ, Nichols WC, Griffith A, Hattori N, Leppert D, Watts R, Zabetian CP, Foroud TM, Farrer MJ, Brice A, Middleton L, Hentati F. Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations. Arch Neurol 63: 1250-4, 2006 (PubMed ID: 16966502) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 88 | |
|
Papapetropoulos S, Singer C, Ross OA, Toft M, Johnson JL, Farrer MJ, Mash DC. Clinical heterogeneity of the LRRK2 G2019S mutation. Arch Neurol 63: 1242-6, 2006 (PubMed ID: 16966501) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 93 | |
|
Carmine Belin A, Westerlund M, Sydow O, Lundströmer K, Håkansson A, Nissbrandt H, Olson L, Galter D. Leucine-rich repeat kinase 2 (LRRK2) mutations in a Swedish Parkinson cohort and a healthy nonagenarian. Mov Disord 21: 1731-4, 2006 (PubMed ID: 16817197) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 69 | |
|
Goldwurm S, Zini M, Di Fonzo A, De Gaspari D, Siri C, Simons EJ, van Doeselaar M, Tesei S, Antonini A, Canesi M, Zecchinelli A, Mariani C, Meucci N, Sacilotto G, Cilia R, Isaias IU, Bonetti A, Sironi F, Ricca S, Oostra BA, Bonifati V, Pezzoli G. LRRK2 G2019S mutation and Parkinson's disease: a clinical, neuropsychological and neuropsychiatric study in a large Italian sample. Parkinsonism Relat Disord 12: 410-9, 2006 (PubMed ID: 16750929) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 87 | |
|
Zabetian CP, Hutter CM, Yearout D, Lopez AN, Factor SA, Griffith A, Leis BC, Bird TD, Nutt JG, Higgins DS, Roberts JW, Kay DM, Edwards KL, Samii A, Payami H. LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago. Am J Hum Genet 79: 752-8, 2006 (PubMed ID: 16960813) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 101 | |
|
Rajput A, Dickson DW, Robinson CA, Ross OA, Dächsel JC, Lincoln SJ, Cobb SA, Rajput ML, Farrer MJ. Parkinsonism, Lrrk2 G2019S, and tau neuropathology. Neurology 67: 1506-8, 2006 (PubMed ID: 17060589) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 97 | |
|
Spanaki C, Latsoudis H, Plaitakis A. LRRK2 mutations on Crete: R1441H associated with PD evolving to PSP. Neurology 67: 1518-9, 2006 (PubMed ID: 17060595) |
|
|
LRRK2:
(Arg1441His)
(Gly2019Ser)
|
|
ID: 81 | |
|
Clark LN, Wang Y, Karlins E, Saito L, Mejia-Santana H, Harris J, Louis ED, Cote LJ, Andrews H, Fahn S, Waters C, Ford B, Frucht S, Ottman R, Marder K. Frequency of LRRK2 mutations in early- and late-onset Parkinson disease. Neurology 67: 1786-91, 2006 (PubMed ID: 17050822) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 70 | |
|
Funalot B, Nichols WC, Pérez-Tur J, Mercier G, Lucotte G. Genetic screening for two LRRK2 mutations in French patients with idiopathic Parkinson's disease. Genet Test 10: 290-3, 2006 (PubMed ID: 17253937) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 73 | |
|
Pchelina SN, Yakimovskii AF, Ivanova ON, Emelianov AK, Zakharchuk AH, Schwarzman AL. G2019S LRRK2 mutation in familial and sporadic Parkinson's disease in Russia. Mov Disord 21: 2234-6, 2006 (PubMed ID: 2234-6) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 78 | |
|
Punia S, Behari M, Govindappa ST, Swaminath PV, Jayaram S, Goyal V, Muthane UB, Juyal RC, Thelma BK. Absence/rarity of commonly reported LRRK2 mutations in Indian Parkinson's disease patients. Neurosci Lett 409: 83-8, 2006 (PubMed ID: 17052850) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 79 | |
|
Scholz S, Mandel RJ, Fernandez HH, Foote KD, Rodriguez RL, Barton E, Munson S, Singleton A, Okun MS. LRRK2 mutations in a clinic-based cohort of Parkinson's disease. Eur J Neurol 13: 1298-301, 2006 (PubMed ID: 17116211) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 123 | |
|
Dächsel JC, Mata IF, Ross OA, Taylor JP, Lincoln SJ, Hinkle KM, Huerta C, Ribacoba R, Blazquez M, Alvarez V, Farrer MJ. Digenic parkinsonism: investigation of the synergistic effects of PRKN and LRRK2. Neurosci Lett 410: 80-4, 2006 (PubMed ID: 17095157) |
|
|
LRRK2:
(Arg1441Gly)
(Gly2019Ser)
|
|
ID: 106 | |
|
Deng H, Le W, Guo Y, Hunter CB, Xie W, Huang M, Jankovic J. Genetic analysis of LRRK2 mutations in patients with Parkinson disease. J Neurol Sci 251: 102-6., 2006 (PubMed ID: 17097110) |
|
|
LRRK2:
(Arg1441Gly)
(Gly2019Ser)
|
|
ID: 71 | |
|
Ishihara L, Gibson RA, Warren L, Amouri R, Lyons K, Wielinski C, Hunter C, Swartz JE, Elango R, Akkari PA, Leppert D, Surh L, Reeves KH, Thomas S, Ragone L, Hattori N, Pahwa R, Jankovic J, Nance M, Freeman A, Gouider-Khouja N, Kefi M, Zouari M, Ben Sassi S, Ben Yahmed S, El Euch-Fayeche G, Middleton L, Burn DJ, Watts RL, Hentati F. Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families. Mov Disord 22: 55-61, 2007 (PubMed ID: 17115391) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 116 | |
|
Xiromerisiou G, Hadjigeorgiou GM, Gourbali V, Johnson J, Papakonstantinou I, Papadimitriou A, Singleton AB. Screening for SNCA and LRRK2 mutations in Greek sporadic and autosomal dominant Parkinson's disease: identification of two novel LRRK2 variants. Eur J Neurol 14: 7-11, 2007 (PubMed ID: 17222106) |
|
|
LRRK2:
(Ala211Val)
(Lys544Glu)
(Gly2019Ser)
|
|
ID: 126 | |
|
Giordana MT, D'Agostino C, Albani G, Mauro A, Di Fonzo A, Antonini A, Bonifati V. Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371Val mutation. Mov Disord 22: 275-8, 2007 (PubMed ID: 17149743) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 109 | |
|
Cossu G, van Doeselaar M, Deriu M, Melis M, Molari A, Di Fonzo A, Oostra BA, Bonifati V. LRRK2 mutations and Parkinson's disease in Sardinia--A Mediterranean genetic isolate. Parkinsonism Relat Disord 13: 17-21, 2007 (PubMed ID: 17064949) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 102 | |
|
Lesage S, Janin S, Lohmann E, Leutenegger AL, Leclere L, Viallet F, Pollak P, Durif F, Thobois S, Layet V, Vidailhet M, Agid Y, Dürr A, Brice A; French Parkinson's Disease Genetics Study Group, Bonnet AM, Borg M, Broussolle E, Damier P, Destée A, Martinez M, Penet C, Rasco O, Tison F, Tranchan C, Vérin M. LRRK2 exon 41 mutations in sporadic Parkinson disease in Europeans. Arch Neurol 64: 425-30, 2007 (PubMed ID: 17353388) |
|
|
LRRK2:
(Tyr2006His)
(Gly2019Ser)
(Thr2031Ser)
|
|
ID: 118 | |
|
Civitelli D, Tarantino P, Nicoletti G, Cirò Candiano IC, Annesi F, De Marco EV, Carrideo S, Rocca FE, Condino F, Spadafora P, Pugliese P, D'Asero S, Morelli M, Paglionico S, Annesi G, Quattrone A. LRRK2 G6055A mutation in Italian patients with familial or sporadic Parkinson's disease. Clin Genet 71: 367-70, 2007 (PubMed ID: 17470139) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 132 | |
|
Illarioshkin SN, Shadrina MI, Slominsky PA, Bespalova EV, Zagorovskaya TB, Bagyeva GKh, Markova ED, Limborska SA, Ivanova-Smolenskaya IA. A common leucine-rich repeat kinase 2 gene mutation in familial and sporadic Parkinson's disease in Russia. Eur J Neurol 14: 413-7, 2007 (PubMed ID: 17388990) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 115 | |
|
Goldwurm S, Zini M, Mariani L, Tesei S, Miceli R, Sironi F, Clementi M, Bonifati V, Pezzoli G. Evaluation of LRRK2 G2019S penetrance: relevance for genetic counseling in Parkinson disease. Neurology 68: 1141-3, 2007 (PubMed ID: 17215492) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 133 | |
|
Dächsel JC, Ross OA, Mata IF, Kachergus J, Toft M, Cannon A, Baker M, Adamson J, Hutton M, Dickson DW, Farrer MJ. Lrrk2 G2019S substitution in frontotemporal lobar degeneration with ubiquitin-immunoreactive neuronal inclusions. Acta Neuropathol 113: 601-6, 2007 (PubMed ID: 17151837) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 138 | |
|
Huang Y, Halliday GM, Vandebona H, Mellick GD, Mastaglia F, Stevens J, Kwok J, Garlepp M, Silburn PA, Horne MK, Kotschet K, Venn A, Rowe DB, Rubio JP, Sue CM. Prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease. Mov Disord 22: 982-9, 2007 (PubMed ID: 17427941) |
|
|
LRRK2:
(Arg1441His)
(Ala1442Pro)
(Gly2019Ser)
|
|
ID: 114 | |
|
Gaig C, Martí MJ, Ezquerra M, Rey MJ, Cardozo A, Tolosa E. G2019S LRRK2 mutation causing Parkinson's disease without Lewy bodies. J Neurol Neurosurg Psychiatry 78: 626-8, 2007 (PubMed ID: 17210620) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 105 | |
|
Ferreira JJ, Guedes LC, Rosa MM, Coelho M, van Doeselaar M, Schweiger D, Di Fonzo A, Oostra BA, Sampaio C, Bonifati V. High prevalence of LRRK2 mutations in familial and sporadic Parkinson's disease in Portugal. Mov Disord 22: 1194-201, 2007 (PubMed ID: 17469194) |
|
|
LRRK2:
(Arg1441His)
(Gly2019Ser)
|
|
ID: 103 | |
|
Perez-Pastene C, Cobb SA, Díaz-Grez F, Hulihan MM, Miranda M, Venegas P, Godoy OT, Kachergus JM, Ross OA, Layson L, Farrer MJ, Segura-Aguilar J. Lrrk2 mutations in South America: A study of Chilean Parkinson's disease. Neurosci Lett 422: 193-7, 2007 (PubMed ID: 17614198) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 122 | |
|
Orr-Urtreger A, Shifrin C, Rozovski U, Rosner S, Bercovich D, Gurevich T, Yagev-More H, Bar-Shira A, Giladi N. The LRRK2 G2019S mutation in Ashkenazi Jews with Parkinson disease: is there a gender effect?. Neurology 69: 1595-602, 2007 (PubMed ID: 17938369) |
|
|
LRRK2:
(Leu2005)
(Tyr2018)
(Gly2019Ser)
|
|
ID: 135 | |
|
Nichols WC, Elsaesser VE, Pankratz N, Pauciulo MW, Marek DK, Halter CA, Rudolph A, Shults CW, Foroud T; Parkinson Study Group-PROGENI Investigators. LRRK2 mutation analysis in Parkinson disease families with evidence of linkage to PARK8. Neurology 69: 1737-44, 2007 (PubMed ID: 17804834) |
|
|
LRRK2:
(Glu10Lys)
(Glu334Lys)
(Ser461)
(Leu488)
(Ser827)
(Gln1111His)
(Ile1192Val)
(Pro1542Ser)
(Met1646Thr)
(Leu1795Phe)
(Gly2019Ser)
|
|
ID: 120 | |
|
González-Fernández MC, Lezcano E, Ross OA, Gómez-Esteban JC, Gómez-Busto F, Velasco F, Alvarez-Alvarez M, Rodríguez-Martínez MB, Ciordia R, Zarranz JJ, Farrer MJ, Mata IF, de Pancorbo MM. Lrrk2-associated parkinsonism is a major cause of disease in Northern Spain. Parkinsonism Relat Disord 13: 509-15, 2007 (PubMed ID: 17540608) |
|
|
LRRK2:
(Arg1441Gly)
(Gly2019Ser)
|
|
ID: 110 | |
|
Johnson J, Paisán-Ruíz C, Lopez G, Crews C, Britton A, Malkani R, Evans EW, McInerney-Leo A, Jain S, Nussbaum RL, Foote KD, Mandel RJ, Crawley A, Reimsnider S, Fernandez HH, Okun MS, Gwinn-Hardy K, Singleton AB. Comprehensive screening of a North American Parkinson's disease cohort for LRRK2 mutation. Neurodegener Dis 4: 386-91, 2007 (PubMed ID: 17622782) |
|
|
LRRK2:
(IVS19+5_8delGTAA)
(Pro1542Ser)
(Met1646Thr)
(Gly2019Ser)
(Thr2356Ile)
|
|
ID: 117 | |
|
Lesage S, Leclere L, Lohmann E, Borg M, Ruberg M, Dürr A, Brice A; French Parkinson's Disease Genetics Study Group. Frequency of the LRRK2 G2019S mutation in siblings with Parkinson's disease. Neurodegener Dis 4: 195-8, 2007 (PubMed ID: 17596714) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 134 | |
|
Squillaro T, Cambi F, Ciacci G, Rossi S, Ulivelli M, Malandrini A, Mencarelli MA, Mari F, Renieri A, Ariani F. Frequency of the LRRK2 G2019S mutation in Italian patients affected by Parkinson's disease. J Hum Genet 52: 201-4, 2007 (PubMed ID: 17235449) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 136 | |
|
Bras J, Guerreiro R, Ribeiro M, Morgadinho A, Januario C, Dias M, Calado A, Semedo C, Oliveira C, Hardy J, Singleton A. Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2. BMC Neurol 8: , 2008 (PubMed ID: 18211709) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 139 | |
|
Munhoz RP, Wakutani Y, Marras C, Teive HA, Raskin S, Werneck LC, Moreno D, Sato C, Lang AE, Rogaeva E. The G2019S LRRK2 mutation in Brazilian patients with Parkinson's disease: phenotype in monozygotic twins. Mov Disord 23: 290-4, 2008 (PubMed ID: 17999435) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 161 | |
|
Chen-Plotkin AS, Yuan W, Anderson C, McCarty Wood E, Hurtig HI, Clark CM, Miller BL, Lee VM, Trojanowski JQ, Grossman M, Van Deerlin VM. Corticobasal syndrome and primary progressive aphasia as manifestations of LRRK2 gene mutations. Neurology 70: 521-7, 2008 (PubMed ID: 17914064) |
|
|
LRRK2:
(Arg793Met)
(Leu1165Pro)
(Gly2019Ser)
|
|
ID: 173 | |
|
Pimentel MM, Moura KC, Abdalla CB, Pereira JS, de Rosso AL, Nicaretta DH, Campos M Jr, de Almeida RM, dos Santos JM, Bastos IC, Mendes MF, Maultasch H, Costa FH, Werneck AL, Santos-Rebouças CB. A study of LRRK2 mutations and Parkinson's disease in Brazil. Neurosci Lett 433: 17-21, 2008 (PubMed ID: 18201824) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 156 | |
|
Paisán-Ruíz C, Nath P, Washecka N, Gibbs JR, Singleton AB. Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls. Hum Mutat 29: 485-90, 2008 (PubMed ID: 18213618) |
|
|
LRRK2:
(c.-44G>T)
(Leu119Pro)
(Cys228Ser)
(His275)
(Asn289)
(IVS10-4A>G)
(IVS16-14delT)
(Tyr707)
(Met712Val)
(Ala716Val)
(Lys871Glu)
(IVS25-8delT)
(IVS27-9C>T)
(Pro1262Ala)
(Ala1430)
(IVS30+12delT)
(Arg1514Gln)
(Pro1542Ser)
(Met1646Thr)
(Arg1728His)
(Arg1728Leu)
(IVS37-9A>G)
(Met1869Val)
(Leu1870Phe)
(IVS38+7C>T)
(Gly2019Ser)
(Thr2141Met)
(Arg2143His)
(Gly2170)
(Glu2395Lys)
(Gly2432)
(Leu2466His)
|
|
ID: 154 | |
|
Healy DG, Falchi M, O'Sullivan SS, Bonifati V, Durr A, Bressman S, Brice A, Aasly J, Zabetian CP, Goldwurm S, Ferreira JJ, Tolosa E, Kay DM, Klein C, Williams DR, Marras C, Lang AE, Wszolek ZK, Berciano J, Schapira AH, Lynch T, Bhatia KP, Gasser T, Lees AJ, Wood NW; International LRRK2 Consortium. Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet Neurol 7: 583-90, 2008 (PubMed ID: 18539534) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 146 | |
|
Hulihan MM, Ishihara-Paul L, Kachergus J, Warren L, Amouri R, Elango R, Prinjha RK, Upmanyu R, Kefi M, Zouari M, Sassi SB, Yahmed SB, El Euch-Fayeche G, Matthews PM, Middleton LT, Gibson RA, Hentati F, Farrer MJ.. LRRK2 Gly2019Ser penetrance in Arab-Berber patients from Tunisia: a case-control genetic study. Lancet Neurol 7: 591-4, 2008 (PubMed ID: 18539535) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 147 | |
|
Möller JC, Rissling I, Mylius V, Höft C, Eggert KM, Oertel WH. The prevalence of the G2019S and R1441C/G/H mutations in LRRK2 in German patients with Parkinson's disease. Eur J Neurol 15: 743-5, 2008 (PubMed ID: 18484993) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 152 | |
|
Pchelina SN, Yakimovskii AF, Emelyanov AK, Ivanova ON, Schwarzman AL, Singleton AB. Screening for LRRK2 mutations in patients with Parkinson's disease in Russia: identification of a novel LRRK2 variant. Eur J Neurol 15: 692-6, 2008 (PubMed ID: 18435766) |
|
|
LRRK2:
(Arg1441Cys)
(Val1613Ala)
(Gly2019Ser)
|
|
ID: 155 | |
|
Aguiar P de C, Lessa PS, Godeiro C Jr, Barsottini O, Felício AC, Borges V, Silva SM, Saba RA, Ferraz HB, Moreira-Filho CA, Andrade LA. Genetic and environmental findings in early-onset Parkinson's disease Brazilian patients. Mov Disord 23: 1228-33, 2008 (PubMed ID: 18464276) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 143 | |
|
Gaig C, Ezquerra M, Martí MJ, Valldeoriola F, Muñoz E, Lladó A, Rey MJ, Cardozo A, Molinuevo JL, Tolosa E. Screening for the LRRK2 G2019S and codon-1441 mutations in a pathological series of parkinsonian syndromes and frontotemporal lobar degeneration. J Neurol Sci 270: 94-8, 2008 (PubMed ID: 18353371) |
|
|
LRRK2:
(Arg1441)
(Gly2019Ser)
|
|
ID: 144 | |
|
Marras C, Klein C, Lang AE, Wakutani Y, Moreno D, Sato C, Yip E, Munhoz RP, Lohmann K, Djarmati A, Bi A, Rogaeva E. LRRK2 and Parkin mutations in a family with parkinsonism-Lack of genotype-phenotype correlation. Neurobiol Aging Epub: , 2008 (PubMed ID: 18644660) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 150 | |
|
Change N, Mercier G, Lucotte G. Genetic screening of the G2019S mutation of the LRRK2 gene in Southwest European, North African, and Sephardic Jewish subjects. Genet Test 12: 333-9, 2008 (PubMed ID: 18666856) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 141 | |
|
Djaldetti R, Hassin-Baer S, Farrer MJ, Vilariño-Güell C, Ross OA, Kolianov V, Yust-Katz S, Treves TA, Barhum Y, Hulihan M, Melamed E. Clinical characteristics of Parkinson's disease among Jewish Ethnic groups in Israel. J Neural Transm 115: 1279-84, 2008 (PubMed ID: 18665323) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 169 | |
|
Lesage S, Belarbi S, Troiano A, Condroyer C, Hecham N, Pollak P, Lohman E, Benhassine T, Ysmail-Dahlouk F, Dürr A, Tazir M, Brice A; French Parkinson's Disease Genetics Study Group. Is the common LRRK2 G2019S mutation related to dyskinesias in North African Parkinson disease?. Neurology 71: 1550-2, 2008 (PubMed ID: 18981379) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 166 | |
|
Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Goldwurm S, Pezzoli G, Zini M, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Laramie JM, DeStefano AL, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study. BMC Med 6: , 2008 (PubMed ID: 18986508) |
|
|
LRRK2:
(Arg1441Cys)
(Gly2019Ser)
|
|
ID: 148 | |
|
Santos-Rebouças CB, Abdalla CB, Baldi FJ, Martins PA, Corrêa JC, Gonçalves AP, Cunha MS, Borges MB, Pereira JS, Laks J, Pimentel MM. Co-occurrence of sporadic parkinsonism and late-onset Alzheimer's disease in a Brazilian male with the LRRK2 p.G2019S mutation. Genet Test 12: 471-3, 2008 (PubMed ID: 19072560) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 168 | |
|
Covy JP, Yuan W, Waxman EA, Hurtig HI, Van Deerlin VM, Giasson BI. Clinical and pathological characteristics of patients with leucine-rich repeat kinase-2 mutations. Mov Disord 24: 32-9, 2009 (PubMed ID: 19006185) |
|
|
LRRK2:
(Arg793Met)
(Leu1165Pro)
(Gly2019Ser)
|
|
ID: 177 | |
|
Mellick GD, Siebert GA, Funayama M, Buchanan DD, Li Y, Imamichi Y, Yoshino H, Silburn PA, Hattori N. Screening PARK genes for mutations in early-onset Parkinson's disease patients from Queensland, Australia. Parkinsonism Relat Disord 15: 105-9, 2009 (PubMed ID: 18486522) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 151 | |
|
Barsottini OG, Felício AC, Aguiar Pde C, Godeiro-Junior C, Shih MC, Hoexter MQ, Bressan RA, Ferraz HB, Andrade LA. Clinical and molecular neuroimaging characteristics of Brazilian patients with Parkinson's disease and mutations in PARK2 or PARK8 genes. Arq Neuropsiquiatr 67: 7-11, 2009 (PubMed ID: 19330201) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 188 | |
|
De Rosa A, Criscuolo C, Mancini P, De Martino M, Giordano IA, Pappatà S, Filla A, De Michele G. Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy. Parkinsonism Relat Disord 15: 242-4, 2009 (PubMed ID: 18621566) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 184 | |
|
Hassin-Baer S, Laitman Y, Azizi E, Molchadski I, Galore-Haskel G, Barak F, Cohen OS, Friedman E. The leucine rich repeat kinase 2 (LRRK2) G2019S substitution mutation. Association with Parkinson disease, malignant melanoma and prevalence in ethnic groups in Israel. J Neurol 256: 483-7, 2009 (PubMed ID: 19412725) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 185 | |
|
Patra B, Parsian AJ, Racette BA, Zhao JH, Perlmutter JS, Parsian A. LRRK2 gene G2019S mutation and SNPs [haplotypes] in subtypes of Parkinson's disease. Parkinsonism Relat Disord 15: 175-80, 2009 (PubMed ID: 18752982) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 186 | |
|
Gao L, Gómez-Garre P, Díaz-Corrales FJ, Carrillo F, Carballo M, Palomino A, Díaz-Martín J, Mejías R, Vime PJ, López-Barneo J, Mir P. Prevalence and clinical features of LRRK2 mutations in patients with Parkinson's disease in southern Spain. Eur J Neurol Epub: , 2009 (PubMed ID: 19473361) |
|
|
LRRK2:
(Asp1420Asn)
(Arg1441Gly)
(Gly2019Ser)
|
|
ID: 193 | |
|
Gorostidi A, Ruiz-Martínez J, de Munain AL, Alzualde A, Massó JF. LRRK2 G2019S and R1441G mutations associated with Parkinson's disease are common in the Basque Country, but relative prevalence is determined by ethnicity. Neurogenetics 10: 157-9, 2009 (PubMed ID: 19020907) |
|
|
LRRK2:
(Arg1441Gly)
(Gly2019Ser)
|
|
ID: 145 | |
|
Lesage S, Condroyer C, Lannuzel A, Lohmann E, Troiano A, Tison F, Damier P, Thobois S, Ouvrard-Hernandez AM, Rivaud-Péchoux S, Brefel-Courbon C, Destée A, Tranchant C, Romana M, Leclere L, Dürr A, Brice A. Molecular analyses of the LRRK2 gene in European and North-African autosomal dominant Parkinson's disease. J Med Genet Epub: , 2009 (PubMed ID: 19357115) |
|
|
LRRK2:
(c.-30G>C)
(Ser52Phe)
(Leu119Pro)
(His275)
(Glu334Lys)
(Asn363Ser)
(Val674)
(Ile810Val)
(His1216Arg)
(Arg1325Gln)
(Ile1371Val)
(Thr1410Met)
(IVS30+12delT)
(Arg1441His)
(Pro1542Ser)
(IVS32+14G>A)
(Met1646Thr)
(Gly2019Ser)
(IVS46-14T>A)
(IVS46-8delT)
(Gly2385)
|
|
ID: 179 | |
|
Munhoz RP, Teive HA, Francisco AN, Raskin S, Rogaeva E. Unilateral pallidotomy in a patient with parkinsonism and G2019S LRRK2 mutation. Mov Disord 24: 791-2, 2009 (PubMed ID: 19012346) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 190 | |
|
Rizzo G, Marconi S, Capellari S, Scaglione C, Martinelli P. Benign tremulous parkinsonism in a patient with dardarin mutation. Mov Disord Epub: , 2009 (PubMed ID: 19373934) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 194 | |
|
Floris G, Cannas A, Solla P, Murru MR, Tranquilli S, Corongiu D, Rolesu M, Cuccu S, Sardu C, Marrosu F, Marrosu MG. Genetic analysis for five LRRK2 mutations in a Sardinian parkinsonian population: importance of G2019S and R1441C mutations in sporadic Parkinson's disease patients. Parkinsonism Relat Disord 15: 277-80, 2009 (PubMed ID: 18805725) |
|
|
LRRK2:
(Arg1441Cys)
(Gly2019Ser)
|
|
ID: 178 | |
|
Zabetian CP, Yamamoto M, Lopez AN, Ujike H, Mata IF, Izumi Y, Kaji R, Maruyama H, Morino H, Oda M, Hutter CM, Edwards KL, Schellenberg GD, Tsuang DW, Yearout D, Larson EB, Kawakami H. LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease. Mov Disord 24: 1034-41, 2009 (PubMed ID: 19343804) |
|
|
LRRK2:
(Arg1067Gln)
(Pro1446Leu)
(Val1450Ile)
(Gly2019Ser)
(Gly2385Arg)
|
|
ID: 182 | |
|
Mata IF, Cosentino C, Marca V, Torres L, Mazzetti P, Ortega O, Raggio V, Aljanati R, Buzó R, Yearout D, Dieguez E, Zabetian CP. LRRK2 mutations in patients with Parkinson's disease from Peru and Uruguay. Parkinsonism Relat Disord 15: 370-3, 2009 (PubMed ID: 18980856) |
|
|
LRRK2:
(Arg1441Gly)
(Gly2019Ser)
|
|
ID: 180 | |
|
Pirkevi C, Lesage S, Condroyer C, Tomiyama H, Hattori N, Ertan S, Brice A, Basak AN. A LRRK2 G2019S mutation carrier from Turkey shares the Japanese haplotype. Neurogenetics 10: 271-3, 2009 (PubMed ID: 19172321) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 187 | |
|
Abdalla-Carvalho CB, Santos-Rebouças CB, Guimarães BC, Campos M, Pereira JS, Zuma de Rosso AL, Nicaretta DH, Marinho E Silva M, Mendonça Dos Santos J, Pimentel MM.. Genetic analysis of LRRK2 functional domains in Brazilian patients with Parkinson's disease. Eur J Neurol Epub: , 2010 (PubMed ID: 20443975) |
|
|
LRRK2:
(Arg1398)
(Thr1410Met)
(Gly2019Ser)
(Cys2139Ser)
(Tyr2189Cys)
|
|
ID: 425 | |
|
Bardien S, Marsberg A, Keyser R, Lombard D, Lesage S, Brice A, Carr J.. LRRK2 G2019S mutation: frequency and haplotype data in South African Parkinson's disease patients. J Neural Transm Epub: , 2010 (PubMed ID: 20544233) |
|
|
LRRK2:
(Gly2019Ser)
|
|
ID: 426 | |
Mutation color legend:
Red: mutation is pathogenic
Orange: pathogenic nature is unclear
Green: mutation is not pathogenic
 |
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